Endoscopic diagnosis and management of pleural effusion in malignant pleural mesothelioma

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Diagnosis and management of malignant pleural effusion.

Malignant pleural effusions (MPEs) are an important clinical problem in patients with neoplastic disease. They can occur as the initial presentation of cancer, a delayed complication in patients with previously diagnosed malignancies, or the first manifestation of cancer recurrence after therapy. Common cancer types causing MPEs include lymphomas, mesotheliomas, and carcinomas of the breast, lu...

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The Role of Immunohistochemistry Studies in Distinguishing Malignant Mesothelioma from Metastatic Lung Carcinoma in Malignant Pleural Effusion

Background and Objective: Early diagnosis of malignant pleural mesothelioma (MPM) is the key point of its treatment. The main problem is the precise diagnosis of mesothelioma and its differentiation from metastatic lung adenocarcinoma. Mesothelioma exhibits complex immunohistochemical characteristics. The aim of this study was to study hybrid immunohistochemistry in the differe...

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Management of Malignant Pleural Effusion

Classically described; pleural effusion is the accumulation of fluid in the pleural gap that may be caused by any reason [4]. If there is an evidence of invasion by the tumor or any malignant cells detected in this fluid, it is described as malignant pleural effusion. Although there has been no epidemiologic study with respect to pleural effusion yet, it is a common clinic problem which is esti...

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Diagnosis and treatment of malignant pleural mesothelioma.

There are three major challenges in the diagnosis of malignant pleural mesothelioma: mesothelioma must be distinguished from benign mesothelial hyperplasia; malignant mesothelioma (and its subtypes) must be distinguished from metastatic carcinoma; and invasion of structures adjacent to the pleura must be demonstrated. The basis for clarifying the first two aspects is determination of a panel of...

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There are three major challenges in the diagnosis of malignant pleural mesothelioma: mesothelioma must be distinguished from benign mesothelial hyperplasia; malignant mesothelioma (and its subtypes) must be distinguished from metastatic carcinoma; and invasion of structures adjacent to the pleura must be demonstrated. The basis for clarifying the first two aspects is determination of a panel of...

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ژورنال

عنوان ژورنال: Journal of Thoracic Disease

سال: 2018

ISSN: 2072-1439,2077-6624

DOI: 10.21037/jtd.2017.09.142